Successful first installation of AOD microscope in China

2018-11-15 read:163

On 13 Nov, the first unit of Femto3D-AcoustoOptic microscope (AOD) from Femtoncis was successfully installed in Xinxiang Medical University.

Femto3D-AcoustoOptic microscope is the first fast, 3D, two-photon microscope on the market. The microscope is capable of scanning neuronal, dendritic, and other neuropil activities by about one million faster speed as compared to previous realizations within a large (about cubic millimeter) scanning volume with preserved two-photon resolution. The microscope, using electrically tunable lenses, can focus the excitation point with up to 53 kHz speed to any 3D location under the objective without mechanical restrictions reaching sub-millisecond temporal resolution in a millimeter z-dimension scanning range.ments has been started and Terabytes of images has been stored.
Thanks to large aperture AO deflectors, angular dispersion compensation and diffraction-based optical modelling, in the case of in vivo measurement, the size of the scanning volume is 500 x 500 x 700 μm3, while it is 650 x 650 x 700 μm3 under in vitro conditions. The transmission of the AODs have been improved for longer, 850-950 nm wavelengths supporting effective GCaMP imaging in the deep tissues. The imaging depth is different in the cases of the types of the biological labelling and it is depends also on the power of the laser source.



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